Pharmacy Automation Journey: BWH’s Wins, Lessons, and Future Steps

The evolution and implementation of pharmacy robotic automated systems within hospital settings have seen significant advancements over the past three decades. Brigham and Women’s Hospital (BWH) in Boston has been at the forefront of this transformation, navigating the complexities of technology integration to enhance patient safety and labor efficiency. This article delves into BWH’s journey, highlighting their experiences, challenges, and strategic steps toward successful automation.

The Early Days of Automation at BWH

Initial Adoption and Challenges

BWH’s journey with pharmacy automation began after a compounding error attributed to human error. This incident led to the introduction of their first syringe-filling robot, the IntelliFill i.v. (Sigma Equipment). Operated by two certified pharmacy technicians, this robot managed inventory, logged production, and monitored data. Despite its efficiency and reliability, the robot had drawbacks, such as reliance on proprietary syringes and the need for manual capping, which increased the workload. The program was generally successful until the vendor stopped supporting the product in 2014.

Throughout this period, the hospital acknowledged the pressing need to enhance their systems to reduce human error. While the IntelliFill i.v. featured promising capabilities, it fell short in adaptability, demanding manual capping and the use of specific syringes that constrained its efficacy. The reliance on unique consumables and proprietary systems posed significant operational hurdles, leading to eventual limitations in the broader adoption of automation. Ultimately, the discontinuation of vendor support highlighted the necessity for robust vendor partnerships in maintaining and evolving automated solutions.

Experimentation with New Systems

Between 2012 and 2017, BWH experimented with four additional robotic and automated compounding systems: two generations of chemotherapy robots (CytoCare [Health Robotics] and i.v.Station ONCO [Omnicell]), an IV batch compounding robot (i.v.Station [Omnicell]), and an IV workflow assist device (i.v.Soft Assist [Omnicell]). These systems came with expansive safety features like gravimetrics, barcode scanning, and visual recognition and interfaced with the hospital’s CPOE system. However, they faced limitations such as product availability and specificity issues, causing delays in production when substitutes were not available.

The frequent trial and replacement of these systems underscored many challenges intrinsic to integrating advanced technology in hospital settings. The issues ranged from specific National Drug Code (NDC) dependency to challenges in configuring new products, revealing that even the most advanced automated systems required significant tweaking to align with real-world hospital pharmacy needs. Nevertheless, each iteration offered learning opportunities, teaching the team about balancing advanced technology with practical workflow integration, albeit often against a backdrop of recurring setbacks.

Lessons Learned from Early Implementations

Device Specificity and Production Delays

Through a review of their eight-year experience with these systems, BWH assessed maximum production for each device. They concluded that the most productive systems were the initial syringe-filling robot and the subsequent batch compounding robot. Key lessons from the early implementation phases included recognizing the significant barrier posed by device specificity. Robots requiring specific drugs and equipment were prone to downtime due to shortages and delays in configuring new products.

This realization underscored that the specificity of robots to certain consumables could be a double-edged sword; although precision in dispensing is crucial, an over-reliance on particular items or configurations can significantly stymie production. BWH’s experience with these automation technologies highlighted the critical importance of flexibility and having a responsive inventory management system, capable of swiftly adapting to fluctuating supplies and configurations without compromising operational continuity.

Balancing Accuracy and Efficiency

Another noteworthy point was that while accuracy-enhancing features like gravimetrics, volumetrics, and optical scanning were beneficial, they could slow down production if needed for all preparations. The inability to manage these features flexibly necessitated a keen understanding of which steps were essential for different types of preparations. This balance between accuracy and production efficiency was critical for optimizing the benefit of these systems.

Ensuring a seamless, uninterrupted flow of pharmacy operations requires a judicious balance between the utmost accuracy in compounding and efficient, high-throughput production. BWH’s insights pointed to the necessity for a robust strategy—deployed with an understanding of the nuanced requirements of different medical preparations. These strategies ensure that even while striving for the highest accuracy, the day-to-day operational efficiencies remain unobstructed, leading to a systemic proficiency in handling varying demands.

Strategic Re-adoption and Future Steps

Resuming Automation with Caution

After encountering multiple challenges with early IV robot adoption, BWH spent six years (2017-2023) without such technology. During this period, significant outsourcing increased costs, prompting BWH to reassess their approach. Resuming their journey with caution, in January 2023, BWH acquired a newer-generation IV batch robot, KIRO Fill (Kiro Grifols SL), to compound rocuronium. While it presented a smaller footprint and configurations for both syringes and bags and employed gravimetrics and barcode scanning, it lacked a labeling function, requiring manual intervention.

Conscious of past learnings, BWH’s cautious return to automation marked a pivotal juncture. The KIRO Fill robot represented a strategic investment focused on enhancing precision with minimized footprint and flexible compounding options. However, the absence of an integrated labeling function once again foregrounded the inherent trade-offs in adopting new technology—balancing cutting-edge automation with the necessity for human intervention in certain steps. This strategic pivot underscored the significance of targeted application and phased integration in achieving sustainable automation.

Integration of IV Workflow Assist Device

In March 2024, BWH integrated an IV Workflow Assist Device, IVX Workflow (Omnicell), for patient-specific doses, operational across three shifts, seven days a week. The hospital chose the ten most frequently prepared drugs to gauge success, finding encouraging results and better production numbers than previous versions. This phased, cautious re-adoption starting with high-volume and significant cost-saving initiatives indicated a strategic approach to leveraging automation while addressing prior challenges.

This particular adoption phase highlighted an incremental yet steady approach to automation resumption. By prioritizing high-frequency medications and focusing on measurable improvements in output, BWH illustrated a blueprint for progressive automation integration. Their operational strategy ensured that while leveraging technological advancements, they addressed previous challenges pragmatically, embedding flexibility and adaptability within their automated processes. This underscored a methodology that balanced technical innovation with practical, on-the-ground applicability.

Overarching Trends and Consensus Viewpoints

Importance of Project Management and Maintenance

Throughout this journey, several overarching trends and consensus viewpoints emerged. The integration of robotic systems significantly contributes to safety and efficiency in pharmacy operations, but it comes with specific implementation challenges. Device specificity poses a primary barrier to seamless operations, while detailed project management, preventive maintenance, and dedicated resources are essential to overcoming these barriers. Preventive maintenance was highlighted as essential, likened to regular automotive maintenance, to ensure consistent device performance and account for necessary downtime.

The criticality of project management cannot be understated in this context. Successful automation hinges on ongoing oversight, prompt troubleshooting, and seamless production flows. At BWH, dedicated resources and significant investments in regular maintenance routines played a pivotal role in ensuring that their automated systems operated smoothly and with minimal downtimes. This commitment underscores a vital takeaway: investment in supportive infrastructure often predicates the success or failure of automation initiatives.

Balancing Innovation and Practical Application

Over the past three decades, the development and adoption of pharmacy robotic automated systems in hospital environments have made substantial progress. A prime example of this evolution can be seen at Brigham and Women’s Hospital (BWH) in Boston. BWH has been a pioneering force in this field, adeptly handling the intricate process of integrating advanced technology to boost both patient safety and labor efficiency. This article explores the journey BWH has undertaken, shedding light on their experiences with automation, the challenges they faced, and the strategic measures they employed to achieve successful implementation. Their efforts showcase how a hospital can effectively navigate the wave of technological innovation to deliver improved healthcare outcomes. Through a meticulous approach and a focus on overcoming obstacles, BWH has managed to set a precedent in the use of pharmacy robotics, underpinning the hospital’s commitment to continuous improvement and excellence in patient care.

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